2022 ASM Program

Monday November 14, 2022

08.30-16.30 Park Room
Surgical Workshop: The Guts of GI Surgery from Data to Distant Disease
08.30–10.00 Park Room
Surgical Workshop: The Guts of GI Surgery from Data to Distant Disease Artificial Intelligence and Big Data This session explores the big topic of digitising health and big data topics from our expert invited faculty. We explore the emerging role of AI in surgery and hear about the latest research in this space. Presenters:
Tim Pawlik
Saxon Connor – Digitising healthcare: a journey toward our future Henry Badgery – The emerging role of artificial intelligence in GI surgery Chairs: Jonathan Koea & Mandivavarira Maundura
10.00–10.30
Morning Tea Welcome and introduction * Acknowledgement of Country – Gail Garvey Karakia – George Laking Chairs: Bruce Cheek & Chris Brooks
10.30–12.00 Park Room
Surgical Workshop: The Guts of GI Surgery from Data to Distant Disease Minimally Invasive GI Surgery and Other Adjunctive Techniques This session explores the role of the advanced endoscopist in managing upper GI cancers, robotic HPB surgery and delves into “to TME or not to TME” and the impact of TNT in rectal cancers. We explore the role of adjuncts in managing liver metastases from ablation, TACE, and SIRT and when to consider which modality. Presenters: David Cavallucci – Robotics HPB surgery Charbel Sandroussi – When do I use my adjunct and which one do I use? MWA, TACE, RFA, SIRT Matt Morgan – To TME or not to TME and the impact of TNT Michael Bourke Chairs: Suellyn Centauri, Simon Wilkins & Jas Samra
12.00–13.00
Lunch Case presentations and panel discussion: Strategies to extend access and increase equity in clinical trials * Presenters: CALD populations – Reema Harrison
Aboriginal and Torres Strait Islander people – Gail Garvey Māori population, data sovereignty and biological samples – George Laking Trial operations – Anne Woollett
13.00–14.30 Park Room
Surgical Workshop: The Guts of GI Surgery from Data to Distant Disease Colorectal Metastases Hear from leading experts on the management of peritoneal metastases, the role of surgery in multi-site colorectal metastases and sequencing of treatment in metastatic colorectal cancer. Presenters:
Cherry Koh – Peritoneal Metastases
Tim Pawlik – Sequencing: Liver vs Bowel vs Synchronous Sandy Heriot – Role of Surgery in Multi-site Metastases Chairs: Kaye Bowers & Charbel Sandroussi
14.30–15.00
Afternoon Tea Welcome back introduction * Chairs: Jan Mumford & Evonne Tim
15.00-16.30 Park Room
Surgical Workshop: The Guts of GI Surgery from Data to Distant Disease Pearls and Barriers to Surgical Engagement in AGITG Trials Join us as we explore lessons learnt here and overseas from experts and how we can reduce barriers and improve equity to trial access for our patients. Hear a personal account of an extraordinary patient journey and then explore how we can do better in engaging in surgical trials in Australasia in a panel discussion and make this accessible for all patients. Presenters: Mark Smithers: Secrets of a successful surgical trial. Tim Pawlik: George Laking: Ensuring trials address the population most at risk David Downs: What do patients want and experience in clinical trials. A patient perspective. Panel discussion led by Mark Smithers and Jonathan Koea
Panellists:
1. Daniel Croagh
2. Nick O’Rourke
3. David Cavallucci
4. Kate Wilson
5. David Clark
Chairs: Mark Smithers & Jonathan Koea
10.00-15.00 State Room 3
Combined Consumer and Study Coordinator Forum: Extending Access and Increasing Equity
10.00-10.30 State Room 1 & 2
Welcome Morning Tea *
10.30-10.40 State Room 1 & 2
Combined Consumer and Study Coordinator Forum Welcome and introduction Acknowledgement of Country – Gail Garvey Karakia – George Laking Chairs: Bruce Cheek & Chris Brooks
10.40-11.00 State Room 1 & 2
Combined Consumer and Study Coordinator Forum Big data and artificial intelligence: How they apply to clinical trials Presenter: Peter Summons (virtual)
11.00-12.00 State Room 1 & 2
Combined Consumer and Study Coordinator Forum Case presentations and panel discussion: Strategies to extend access and increase equity in clinical trials Presenters: CALD populations – Reema Harrison Aboriginal and Torres Strait Islander people – Gail Garvey Māori population, data sovereignty and biological samples – George Laking Trial operations – Anne Woollett
12.00-12.30 State Room 3
Lunch *
12.30-12.35 State Room 1 & 2
Combined Consumer and Study Coordinator Forum Welcome back introduction Chairs: Jan Mumford & Evonne Tim
12.35-13.30 State Room 1 & 2
Combined Consumer and Study Coordinator Forum Panel discussion with Q&A Panellists: Peter Summons Reema Harrison Gail Garvey George Laking Anne Woollett Chairs: Jan Mumford & Evonne Tim
13.30-13.40 State Room 3
Afternoon Tea Session 4: Subsequent line options and novel therapies * Mayer, 2015, RECOURSE Grothey, 2017, CORRECT Andre, 2020, KN177 Kopetz, 2019, BEASON, Tabernero, 2021, BEACON updated analysis Siena, 2021, DESTINY CRC01 Discussion with Preceptors Virtual MDT Career pathways Feedback and close Convenor: Genni Newnham
13.40-13.45 State Room 1 & 2
Combined Consumer and Study Coordinator Forum Welcome back introduction Chairs: Marlyse Debrincat & Roslynn Murphy
13.45-14.10 State Room 1 & 2
Combined Consumer and Study Coordinator Forum Genetic testing and personalised medicine Presenter: Lara Lipton
14.10–14.35 State Room 1 & 2
Combined Consumer and Study Coordinator Forum Value-adding substudies Presenter: Richard De Abreu Lourenço
14.35–15.00 State Room 1 & 2
Combined Consumer and Study Coordinator Forum Q&A Chairs: Marlyse Debrincat & Roslynn Murphy
10.00-17.00 | AEDT 12.00-19.00 | NZST
Preceptorship in Advanced Colorectal Cancer
09.30–10.00 11.30-12.00
Arrival Morning Tea *
10.00-11.10 | AEDT 12.00-13.10 | NZST
Preceptorship in Advanced Colorectal Cancer Session 1: Diagnostic/molecular markers Yaeger, 2018, Cancer Cell Vakiani, 2012, JCO Stadler, 2016, JCO Cocco, 2019, Cancer Res Siena, 2018, Ann Oncol Raghav, 2018, JCO Precision Oncol Discussion with Preceptors Convenor: Jeanne Tie
11.10–11.20 13.10-13.20
Morning Tea *
11.20-12.45 | AEDT 13.20–14.45 | NZST
Preceptorship in Advanced Colorectal Cancer Session 2: Resectable metastatic disease with curative intent Nordlinger, 2008, Lancet (EPOC), also see long-term results published in 2013 Primrose, 2014, Lancet Onc, (New EPOC), also see long-term results published in 2020 Kanemitsu, 2021, JCO - Cytoreductive surgery + HIPEC de Cuba, 2013, Cancer Treat Rev Goere, 2020, Lancet Onc (PROPHYLOSHIP-PRODIGE 15) Quenet, 2021, Lancet Onc (PRODIGE 7) - Pulmonary metastatic disease Milosevic, 2020, Colorectal Disease Discussion with Preceptors, wrap-up of the morning sessions Convenor: Chris Jackson
12.43–13.13 14.43–15.13
Lunch *
13.15–14.55 15.15–16.55
Preceptorship in Advanced Colorectal Cancer Session 3: First-line and maintenance treatments in unresectable mCRC Resection of Primary in Patients with Unresectable Synchronous Metastases
Moritani, 2020, JJCO (JCOG 1007)
Sequential / ‘Light’ Chemotherapy
Koopman, 2007, Lancet (CAIRO) Cunningham, 013, Lancet Onc (AVEX) Tebbutt, 2010, JCO (MAX) - First-line Combination Treatments
Heinemann, 2014, Lancet Onc (FIRE-3) Final overall survival published in 2021 Revew by Elez et al Holch, 2017, Eur J Cancer Cremolini, 2020, JCO - Continuous vs Intermittent Maintenance Strategies
Simkens, 2015, Lancet (CAIRO3) Maughan, 2011, MRC COIN-Arm A vx B Adam, 2011, MRC COIN-Arm A vs C Chibaudel, 2009, OPTIMOX2 Discussion with Preceptors Convenor: Chris Karapetis
16.55–17.05 Lake Foyer
Afternoon Tea *
15.05-17.00 17.05-19.00
Preceptorship in Advanced Colorectal Cancer Session 4: Subsequent line options and novel therapies Mayer, 2015, RECOURSE Grothey, 2017, CORRECT Andre, 2020, KN177 Kopetz, 2019, BEASON, Tabernero, 2021, BEACON updated analysis Siena, 2021, DESTINY CRC01 Discussion with Preceptors Virtual MDT Career pathways Feedback and close Convenor: Genni Newnham

Tuesday November 15, 2022

06.45-18.00 | AEDT

Grand Room 7/L

Registration Open

07.15-08.45 | AEDT

State Room

Medical Oncology Keynote Breakfast Session – CRC Focus – real world data, quality of cancer care and disparity of cancer care

RCTs have led to major improvements in outcome for patients with cancer care. However, because access to care, quality of care, and outcomes in routine practice are very different from RCTs there is often a gap between efficacy and effectiveness. This lecture will review how real world data can augment what is known from RCTs and help address the current “value crisis” in oncology.

Presenters:
1. Christopher Booth (virtual) Real world data in colorectal cancer: searching for meaningful cancer care
2. Hui-li Wong

Chairs: Monica Tang & Deme Karikios

07.15-08.45 | AEDT

Lake Room 1 & 2

Radiation Oncology Keynote Breakfast Session – CRC Focus

Presenters:
Trang Pham – Targeting gastrointestinal cancer heterogeneity with MRI and radiotherapy using artificial intelligence
Teng Han Tan

Co-Chairs: Michael Ng & Natalie Collier

07.15-08.45 | AEDT

Lake Room 3 & 4

Surgical Oncology Keynote Breakfast Session – Lower GI Cancer

Presenters:
George Chang (virtual) US approach to locally advanced rectal cancer
Tamara Glyn – Christchurch approach to locally advanced rectal cancer
Kim Chi Phan Thien – Tailored approaches to rectal cancer – Right-sided colonic resection: my perspective

Chairs: Sandy Heriot & Cherry Koh

08.45-09.00

Transition to Plenary Room

09.00-09.05

Plenary Room

Welcome

MC: Julie McCrossin

09.05-09.15

Plenary Room

Welcome to Country

09.15-10.30 | AEDT

Grand Room 1 – 4

Opening Plenary – Big Data, Precision Oncology, Artificial Intelligence

Presenters:
Håvard E Danielsen
Eugene Koay – Leveraging AI, radiomics, and big data tools for pancreatic cancer and cholangiocarcinoma
Tim Pawlik
Panel discussion / Q&A

Chairs: Vicki Whitehall and Michael Lee

10.30-11.00

Trade Hall

Morning Tea

11.00-11.05

Trade Hall

Introduction

MC: Julie McCrossin

11.05-13.00 | AEDT

Grand Room 1 – 4

AGITG Early Colorectal Cancer Trials

• SPAR: Michael Jameson
• DYNAMIC-III & DYNAMIC-Rectal: Jeanne Tie
• ASCOLT: Mark Jeffrey
• RENO: Chris Karapetis
• OXTOX: Janette Vardy
• LICPIC: Stephen Smith
• RoLaCaRT-1/2: Craig Lynch
• POLARiS: Kheng-Seong Ng
AGITG Early Colorectal Cancer Trials Portfolio - How does this fit in to the International Context?

Chairs: Matthew Burge & Hui-Li Wong

13.00-14.00

Trade Hall

Lunch

14.00-14.05

Grand Room 1 – 4

Introduction

MC: Julie McCrossin

14.051-16.00

Grand Room 1 – 4

AGITG Advanced Colorectal Cancer Trials

• ALT-TRACC: Hui-li Wong
• VADER: Fiona Chionh
• RESOLUTE: Julie Chu
• GEENSCREEN 5-FU: Stephen Ackland
• BIOMARCER-2: Shehara Mendis
• FORECAST-1: Margaret Lee
AGITG Advanced Colorectal Cancer Trials Portfolio - How does this fit in to the International Context?

16.00-16.30

Trade Hall

Afternoon Tea

16.30-16.35

Grand Room 1 – 4

Introduction

MC: Julie McCrossin

16.35-18.30 | AEDT

Grand Room 1 – 4

Multidisciplinary Workshop - Locally Advanced Rectal Cancer

Panel Discussion:
Watch/wait vs surgery
short course vs long course and
TNT vs no TNT

Panellists: Lizzy Smyth and Michael Jameson

Chairs: Sina Vatandoust & Ankit Jain

18.30-20.00 | AEDT

Trade Hall

Welcome Reception and Poster Review

Chairs: Jeanne Tie & Amitesh Roy

Wednesday November 16, 2022

07.15-07.25

State Room

Welcome to day and introduction

MC: Julie McCrossin

07.25-08.45 | AEDT

State Room

Translational Research - Keynote Breakfast Session

A better understanding about the initiating pathways of the two principal journeys towards adenomas and ultimately carcinomas in patients of colorectal cancer

Presenters:
Håvard E Danielsen
Bob Coffey (virtual)

Discussion

Chairs: Vicki Whitehall & Nicholas Clemons

08.45-09.00

Transition to Plenary Room

09.00-09.10

Plenary Room

Start of day welcome, housekeeping and introduction to Translational Science Symposium 1

MC: Julie McCrossin

09.10-10.30 | AEDT

Grand Room 1 – 4

Translational Science Symposium1 - Predicting therapeutic outcomes

Presenters:
Marina Pajic
John Lock

Co-Chairs: Phoebe Phillips, Jeff Cuff & Tim Pawlik

10.30-11.00

Trade Hall

Morning Tea

11.00-11.10

Grand Room 1 – 4

Welcome back and introduction to next session

MC: Julie McCrossin

11.10-12.30

Grand Room 1 – 4

Translational Science Symposium 2 - Genomic and implementation, how we might be able to use genomic clinically and what’s happening and what people are trying to develop

Presenters:
Christina Curtis (virtual)
Kortnye Smith

Panel discussion

Chairs: Oliver Sieber & Jan Mumford

12.30-12.45

Transition to Breakout Rooms

12.45-13.45 | AEDT

Grand Room 1 – 4

Special Interest Breakout Session 1

12.45-13.45 | AEDT

State Room 1 & 2

Special Interest Breakout Session 2

12.45-13.45 | AEDT

State Room 3

Special Interest Breakout Session 3

13.45-14.45

Lunch

14.45-14.50

Grand Room 1 – 4

Introduction

MC: Julie McCrossin

14.45-16.30 | AEDT

Grand Room 1 – 4

New Concepts Symposium

16.30-17.00

Trade Hall

Afternoon Tea

17.00-17.05

Grand Room 1 – 4

Introduction

MC: Julie McCrossin

17.05-18.05 | AEDT

Grand Room 1 – 4

Best of the Best Posters and Fast Forward

The AGITG Annual Scientific Meeting accepts abstracts for posters for selection by the Executive Organising Committee. Posters are displayed in the exhibition area. Four posters are chosen for presentation in the Best of the Best Session. Each presenter has seven minutes to present with three minutes for questions. Four posters are also chosen for Fast Forward presentation. Each presenter has three minutes to present with two minutes for questions. The AGITG recognises excellence in the Posters and Fast Forward Sessions at each annual meeting. The winning presenter in the Posters Session receives a $3,500 prize and framed certificate. The winning presenter in the Fast Forward session receives $1,500 and a framed certificate. The Awards are presented at the Annual Scientific Meeting Dinner and details of the Award recipients are published on the AGITG website and in the Annual Report.

Chairs: Jeanne Tie & Amitesh Roy

18.05-18.10

Grand Hall 1 – 4

Wrap-up

MC: Julie McCrossin

18.30-19.30 | AEDT

Trade Hall

AGITG 24th Annual Meeting Reception

19.30-22.30 | AEDT

Grand Room 1 – 4

AGITG 24th Annual Meeting Dinner

Thursday November 17, 2022

07.15-08.45 | AEDT

Park Room

Medical Oncology Keynote Breakfast Session – Immunotherapy in gastroesophageal cancers

Presenters:
Lizzy Smyth
Amitesh Roy

Co-Chairs: Melissa Eastgate & Michael Allen

07.15-08.45 | AEDT

Park Room 3

Radiation Oncology Keynote Breakfast Session – Upper GI Cancer Focus

Presenter:
Eugene Koay

Co-Chairs: Meredith Johnson & Yuvnik Trada

07.15-08.45 | AEDT

Lake Room

Surgical Oncology Keynote Breakfast Session – The latest on gall bladder and pancreatic cancer

Presenters:
Tim Pawlik
Jas Samra
Dan Croagh
Charles Pilgrim

08.45-09.00

Transition to Plenary Room

09.00-09.05

Grand Room 1 – 4

Welcome

MC: Julie McCrossin

09.05-10.50 | AEDT

Grand Room 1 – 4

AGITG Upper GI Cancer Research Session 1

• NEO-IMPACT: Lorraine Chantrill
• ASCEND: Andrew Dean
• DYNAMIC-Pancreas: Belinda Lee
• MASTERPLAN: Andrew Oar
• PALEO: Fiona Day
• NEO-CREATE: Amitesh Roy
• TOPGEAR: Trevor Leong
• INTEGRATE IIa/b: Nick Pavlakis

Chairs: Lara Lipton and Sweet Ping Ng

10.50-11.20

Trade Hall

Morning Tea

11.20-11.25

Grand room 1 – 4

Introduction

MC: Julie McCrossin

11.25-12.30 | AEDT

Grand Room 1 – 4

AGITG Upper GI Cancer Research Session 2

• CONTROL NETs: Nick Pavlakis
• ALT-GIST: John Zalcberg
• ACME ABC: Dan Croagh
Lizzy Smyth - AGITG Upper GI Cancer Research Portfolio - How does this fit into the international context?

Chairs: Ben Lawrence & Shehara Mendis

12:30-12:45

Transition to Breakout Rooms

12.45-13.45 | AEDT

Grand Room 1- 4

Special Interest Breakout Session 4

12.45-13.45 | AEDT

State Rooms 1 & 2

Special Session Breakout Session 5

12.45-13.45 | AEDT

State Room 3

Special Interest Breakout Session 6

12.45-13.45

Surgical Workshop – NETs Workshop

Listen to the experts cover a dedicated neuroendocrine session.

How far can we go with GEP NET resections and when do we abort? Listen to the advances in managing metastatic neuroendocrine tumours and come hear a challenging case of PNET from our invited faculty.

Presenters:
1. Saxon Connor
2. Ben Thomson – Management of NET liver metastases - Does grade matter?
2. Anubhav Mittal

Chairs: Christopher Lim & Ee Jun Ban

13.45–14.30

Lunch

14.30-16.00 | AEDT

Grand Room 1 – 4

Closing Plenary – Reducing barriers to clinical trial participation for disadvantaged and underserved populations – indigenous, CALD & Rural/Remote/Regional

Facilitators: Julie McCrossin & Rob Ramsay

Panel discussion:
Gail Garvey
Reema Harrison
Narayan Karanth
Abhijit Pal
Sabe Sabesan

16.00

Close of ASM

16.15

Bus depart to Airport

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