2022 ASM Program

Monday November 14, 2022

8am AEDT onwards

State Room Foyer

Registration

Enter via the Main Hotel Entrance, take the Lifts to Level One, and follow the signs to the State Room

08.30-16.30 | AEDT Park Room
Surgical Workshop: The Guts of GI Surgery from Data to Distant Disease
08.25–08.30 | AEDT Park Room
Surgical Workshop: The Guts of GI Surgery from Data to Distant Disease Welcome and Acknowledgement of Country Chairs: Manju Chandrasegaram & Jas Samra
08.30–10.00 | AEDT Park Room
Surgical Workshop: The Guts of GI Surgery from Data to Distant Disease Artificial Intelligence and Big Data This session explores the big topic of digitising health and big data topics from our expert invited faculty. We explore the emerging role of AI in surgery and hear about the latest research in this space. Presenters:
Tim Pawlik - Big Data for Big Questions: The Need for a Diversified Approach
Saxon Connor – Digitising healthcare: A Journey Toward our Future Henry Badgery – The Emerging Role of Artificial Intelligence in GI Surgery Chairs: Jonathan Koea & Mandivavarira Maundura
10.00–10.30 | AEDT
Morning Tea Minimally Invasive GI Surgery and Other Adjunctive Techniques * This session explores the role of the advanced endoscopist in managing upper GI cancers, robotic HPB surgery and delves into “to TME or not to TME” and the impact of TNT in rectal cancers. We explore the role of adjuncts in managing liver metastases from ablation, TACE, and SIRT and when to consider which modality. Presenters: David Cavallucci – Robotics HPB Surgery Charbel Sandroussi – When Do I Use My Adjunct and Which One Do I Use? MWA, TACE, RFA, SIRT Matt Morgan – To TME or Not to TME and the impact of TNT Michael Bourke - How I Approach Neoplasia and Early Cancer in the UGI tract Chairs: Suellyn Centauri, Simon Wilkins & Jas Samra
10.30–12.00 | AEDT Park Room
Surgical Workshop: The Guts of GI Surgery from Data to Distant Disease Minimally Invasive GI Surgery and Other Adjunctive Techniques This session explores the role of the advanced endoscopist in managing upper GI cancers, robotic HPB surgery and delves into “to TME or not to TME” and the impact of TNT in rectal cancers. We explore the role of adjuncts in managing liver metastases from ablation, TACE, and SIRT and when to consider which modality. Presenters: David Cavallucci – Robotics HPB Surgery Charbel Sandroussi – When Do I Use My Adjunct and Which One Do I Use? MWA, TACE, RFA, SIRT Matt Morgan – To TME or Not to TME and the impact of TNT Michael Bourke - How I Approach Neoplasia and Early Cancer in the UGI tract Chairs: Suellyn Centauri, Simon Wilkins & Jas Samra
12.00–13.00 | AEDT
Lunch Colorectal Metastases * Hear from leading experts on the management of peritoneal metastases, the role of surgery in multi-site colorectal metastases and sequencing of treatment in metastatic colorectal cancer. Presenters:
Cherry Koh – Peritoneal Metastases
Tim Pawlik – Sequencing Treatment for Synchronous Colorectal Liver Metastasis: is there an Optimal Approach? Sandy Heriot – Role of Surgery in Multi-site Metastases Chairs: Kaye Bowers & Charbel Sandroussi
13.00–14.30 | AEDT Park Room
Surgical Workshop: The Guts of GI Surgery from Data to Distant Disease Colorectal Metastases Hear from leading experts on the management of peritoneal metastases, the role of surgery in multi-site colorectal metastases and sequencing of treatment in metastatic colorectal cancer. Presenters:
Cherry Koh – Peritoneal Metastases
Tim Pawlik – Sequencing Treatment for Synchronous Colorectal Liver Metastasis: is there an Optimal Approach? Sandy Heriot – Role of Surgery in Multi-site Metastases Chairs: Kaye Bowers & Charbel Sandroussi
14.30–15.00 | AEDT
Afternoon Tea Pearls and Barriers to Surgical Engagement in AGITG Trials * Join us as we explore lessons learnt here and overseas from experts and how we can reduce barriers and improve equity to trial access for our patients. Hear a personal account of an extraordinary patient journey and then explore how we can do better in engaging in surgical trials in Australasia in a panel discussion and make this accessible for all patients. Presenters: Mark Smithers - Secrets of a Successful Surgical Trial Tim Pawlik - Barriers to Clinical Trials Among Patients and Providers: Two Different Sides to the Same Coin George Laking - Ensuring Trials Address the Population Most at Risk David Downs - What Do Patients Want and Experience in Clinical Trials. A patient Perspective Panel discussion:
David Cavallucci, David Clark, Daniel Croagh, Nick O’Rourke and Kate Wilson
Chairs: Mark Smithers & Jonathan Koea
15.00-16.30 | AEDT Park Room
Surgical Workshop: The Guts of GI Surgery from Data to Distant Disease Pearls and Barriers to Surgical Engagement in AGITG Trials Join us as we explore lessons learnt here and overseas from experts and how we can reduce barriers and improve equity to trial access for our patients. Hear a personal account of an extraordinary patient journey and then explore how we can do better in engaging in surgical trials in Australasia in a panel discussion and make this accessible for all patients. Presenters: Mark Smithers - Secrets of a Successful Surgical Trial Tim Pawlik - Barriers to Clinical Trials Among Patients and Providers: Two Different Sides to the Same Coin George Laking - Ensuring Trials Address the Population Most at Risk David Downs - What Do Patients Want and Experience in Clinical Trials. A patient Perspective Panel discussion:
David Cavallucci, David Clark, Daniel Croagh, Nick O’Rourke and Kate Wilson
Chairs: Mark Smithers & Jonathan Koea
10.00-15.00 | AEDT State Room 3
Combined Community and Study Coordinator Forum: Experiences and Strategies to Increase Equity in Clincial Trials and Lessons Learned
10.00-10.30 | AEDT State Room 1&2
Welcome Morning Tea *
10.30-10.40 | AEDT State Room 1 & 2
Combined Community and Study Coordinator Forum Welcome and Introduction Chairs: Bruce Cheek & Chris Brooks
10.40-11.00 | AEDT State Room 1&2
Combined Community and Study Coordinator Forum Peter Summons - Big Data and Artificial Intelligence: How they apply to clinical trials ?
11.00-12.00 | AEDT State Room 1&2
Combined Community and Study Coordinator Forum Experiences and strategies to increase equity in clinical trials and lessons learned Presenters: Reema Harrison - CALD populations Gail Garvey - Aboriginal and Torres Strait Islander people George Laking - Māori Population, Data Sovereignty and Biological Samples Anne Woollett - Trial Operations Followed by panel discussion
12.00-12.30 | AEDT State Room 3
Lunch *
12.30-12.35 | AEDT State Room 1&2
Combined Community and Study Coordinator Forum Welcome back Introduction Chairs: Jan Mumford & Evonne Tim
12.35-13.30 | AEDT State Room 1&2
Combined Community and Study Coordinator Forum Panel discussion / Q&A Chairs: Jan Mumford & Evonne Tim
13.30-13.40 | AEDT State Room 3
Afternoon Tea Session 4: Subsequent Line Options and Novel Therapies * Discussion with Preceptors
Virtual MDT
Feedback and Close
Career Pathways
Convenor: Genni Newnham
13.40-13.45 | AEDT State Room 1&2
Combined Community and Study Coordinator Forum Welcome Back and Introduction Chairs: Marlyse Debrincat & Roslynn Murphy
13.45-14.10 | AEDT State Room 1&2
Combined Community and Study Coordinator Forum Lara Lipton - Genetic Testing / Personalised Medicine
14.10–14.35 | AEDT State Room 1&2
Combined Community and Study Coordinator Forum Richard De Abreu Lourenço - Value-adding Sub Studies
14.35–14.55 | AEDT State Room 1&2
Combined Community and Study Coordinator Forum Q&A Chairs: Marlyse Debrincat & Roslynn Murphy
10.00-17.00 | AEDT 12.00-19.00 | NZST
Preceptorship in Advanced Colorectal Cancer
09.30–10.00 | AEDT 11.30-12.00 | NZST
Welcome Morning Tea *
10.00-10.55 | AEDT 12.00-12.55 | NZST
Preceptorship in Advanced Colorectal Cancer Session 1: Diagnostic / Molecular Markers Discussion with Preceptors Convenor: Jeanne Tie
11.10–11.20 | AEDT 13.10-13.20 | NZST
Morning Tea *
11.20-12.45 | AEDT 13.20–14.45 | NZST
Preceptorship in Advanced Colorectal Cancer Session 2: Resectable Metastatic Disease with Curative Intent Discussion with Preceptors, Wrap Up of the Morning Sessions Convenor: Chris Jackson
12.45–13.15 | AEDT 14.45–15.15 | NZST
Lunch *
13.15–14.55 | AEDT 15.15–16.55 | NZST
Preceptorship in Advanced Colorectal Cancer Session 3: First-line and Maintenance Treatments in Unresectable mCRC Discussion with Preceptors Convenor: Chris Karapetis
16.55–15.05 | AEDT Lake Foyer
Afternoon Tea *
15.05-17.00| AEDT 17.05-19.00 | NZST
Preceptorship in Advanced Colorectal Cancer Session 4: Subsequent Line Options and Novel Therapies Discussion with Preceptors
Virtual MDT
Feedback and Close
Career Pathways
Convenor: Genni Newnham

Tuesday November 15, 2022

06.45-18.00 | AEDT

Grand Room 7/L

Registration Open

07.15-08.45 | AEDT

State Room

Medical Oncology Keynote Breakfast Session – CRC Focus – Real World Data, Quality of Cancer Care and Disparity of Cancer Care

RCTs have led to major improvements in outcome for patients with cancer care. However, because access to care, quality of care, and outcomes in routine practice are very different from RCTs there is often a gap between efficacy and effectiveness. This lecture will review how real world data can augment what is known from RCTs and help address the current “value crisis” in oncology.

Presenters:
Christopher Booth - Real World Data in Colorectal Cancer: Searching for Meaningful Cancer Care
Hui-li Wong - Opportunities and Challenges for Using Real World Data in the Australian Setting

Chairs: Monica Tang & Deme Karikios

07.15-08.45 | AEDT

Lake Rooms 1 & 2

Radiation Oncology Keynote Breakfast Session – CRC Focus

This session will examine the current and future use of MRI for the prediction of radiotherapy response in gastrointestinal cancers. The use of artificial intelligence to characterise cancer biologic heterogeneity with MRI and enhance the quality of clinical MRI images. MRI biomarkers could be used to stratify patients for personalised treatment strategies such as ‘watch-and-wait’ and biology-guided adaptive radiotherapy.

Presenters:
Trang Pham – Targeting Gastrointestinal Cancer Heterogeneity with MRI and Radiotherapy Using Artificial Intelligence
Teng Han Tan – Role of MRI staging in Rectal Cancer and Post Therapy Evaluation in Non-operative Management

Chairs: Michael Ng & Natalie Collier

07.15-08.45 | AEDT

Lake Rooms 3 & 4

Surgical Oncology Keynote Breakfast Session – Lower GI Cancer

This session will look at tailoring surgery for colorectal cancer.

Presenters:
George Chang - TNT: Tailoring lateral pelvic Nodal Treatment
Tamara Glyn – Christchurch Approach to Locally Advanced Rectal Cancer
Kim-Chi Phan-Thien – Right-sided Colonic Resection: My Perspective

Chairs: Sandy Heriot & Cherry Koh

08.45-09.00 | AEDT

Transition to Plenary Room

09.00-09.05 | AEDT

Plenary Room

Welcome and Housekeeping

MC: Julie McCrossin

09.05-09.15 | AEDT

Plenary Room

Welcome to Country

09.15-10.30 | AEDT

Grand Room 1–4

Opening Plenary – Big Data, Precision Oncology, Artificial Intelligence

The rise of electronic medical records, artificial intelligence and increased availability of genomic sequencing of tumours introduces a wealth of data beyond traditional clinical risk factors. This session explores how new “data” is being integrated with our daily clinical practice from improved understanding of cancer biology to better tailoring of our treatment approach. Above all, how do we translate the new understanding back to the clinic of today?

Presenters:
Håvard Danielsen - Deep Learning in Cancer Diagnostics and Prognostication
Eugene Koay – Leveraging AI, radiomics, and Big Data Tools for Pancreatic Cancer and Cholangiocarcinoma
Tim Pawlik - Making Clinical and Scientific Sense of Big Data: How “Precise” is Artificial Intelligence

Panel Discussion / Q&A

Chairs: Vicki Whitehall & Michael Lee

10.30-11.00 | AEDT

Trade Hall

Morning Tea

11.00-11.05 | AEDT

Trade Hall

Introduction

MC: Julie McCrossin

11.05-13.00 | AEDT

Grand Room 1–4

AGITG Early Colorectal Cancer Trials

• SPAR: Michael Jameson
• DYNAMIC-III : Jeanne Tie
• ASCOLT: Mark Jeffery
• RENO: Chris Karapetis
• OXTOX: Lorraine Chantrill
• LICPIC: Stephen Smith
• RoLaCaRT-1/2: Craig Lynch
• POLARiS: Kheng-Seong Ng

AGITG Early Colorectal Cancer Trials Portfolio - How does this fit in to the International Context?

Q&A

Chairs: Ben Lawrence & Hui-Li Wong

13.00-14.00 | AEDT

Trade Hall

Lunch

14.00-14.05 | AEDT

Grand Room 1–4

Introduction

MC: Julie McCrossin

14.05-16.00 | AEDT

Grand Room 1–4

AGITG Advanced Colorectal Cancer Trials

• ALT-TRACC: Hui-li Wong
• VADER: Fiona Chionh
• RESOLUTE: Julie Chu
• GENESCREEN 5-FU: Stephen Ackland
• BIOMARCER-2: Shehara Mendis
• FORECAST-1: Margaret Lee

AGITG Advanced Colorectal Cancer Trials Portfolio - How does this fit in to the International Context?

Q&A

Chairs: Jeanne Tie & David Lau

16.00-16.30 | AEDT

Trade Hall

Afternoon Tea

16.30-16.40 | AEDT

Grand Room 1–4

Welcome Back and Introduction

MC: Julie McCrossin

16.40-18.30 | AEDT

Grand Room 1–4

Multidisciplinary Workshop - Locally Advanced Rectal Cancer

Join your colleagues in this case-based discussion on the current management of rectal cancer. Two multidisciplinary panels of experts will debate the cases against each other. Together we will review the role of different treatment approaches such as watch and wait, TNT, induction/consolidation chemotherapy and short course radiotherapy vs long course chemoradiation.

Case Presentations: Sina Vatandoust & Ankit Jain

Presentation: Kirsten Gormly

Panel:
International: Eugene Koay and Lizzy Smyth
National: Tamara Glyn, Michael Jameson, Andrew Oar and Tarik Sammour

Chairs: Sina Vatandoust & Ankit Jain

18.30-20.00 | AEDT

Trade Hall

Welcome Reception and Poster Review

Chairs: Jeanne Tie & Amitesh Roy

Wednesday November 16, 2022

07.15-07.25| AEDT

State Room

Welcome and Introduction

MC: Julie McCrossin

07.25-08.45 | AEDT

State Room

Keynote Breakfast Session

Applying data from driving clinical decisions to defining fundamental mechanisms of GI carcinogenesis

Evidence is everything in precision medicine but it comes in many forms. This session introduces the concept of applying “Big Data” to unravelling mechanism of carcinogenesis from its earliest origins to patient outcome records. When the data are at scale and unbiased interrogation are employed, insights emerge that were unimaginable previously and all parties from patients, clinician, researchers to health systems benefit.

Presenters:
Håvard Danielsen – How to Use Big Data to Dissect the Mechanisms Driving Cancer Progression and Treatment Response
Bob Coffey - Using Deep Sequencing Data to Define the Earliest Stages of Colorectal Cancer

Discussion

Chairs: Vicki Whitehall & Nicholas Clemons

08.45-09.00 | AEDT

Transition to Plenary Room

09.00-09.10 | AEDT

Plenary Room

Introduction

MC: Julie McCrossin

09.10-10.30 | AEDT

Grand Room 1–4

Translational Science Symposium One - Predicting Therapeutic Outcomes Down to the Single Cell and on to the Single Person

Evidence of disease-relapse, therapeutic response and predictions of patient outcomes will be covered by a broad spectrum of researchers focused on GI cancers, employing data sets from small to big, and from genes to patient populations.

Presenters:
Iain Beehuat Tan- Single cell RNAseq – Delving Deep into Consensus Molecular Subtypes
Marina Pajic - Understanding and Targeting the Dynamic Cellular Ecosystem of Pancreatic Cancer
John Lock - Towards Longitudinal Precision Diagnostics with Multiplexed Cellular Imaging and Deep Learning on Liquid Biopsy Samples

Chairs: Phoebe Phillips, Jeff Cuff & Tim Pawlik

10.30-11.00 | AEDT

Trade Hall

Morning Tea

11.00-11.10 | AEDT

Grand Room 1–4

Welcome back and Introduction

MC: Julie McCrossin

11.10-12.30 | AEDT

Grand Room 1–4

Translational Science Symposium Two - Genomics and Implementation, How to use Genomics Clinically, with Equity and Impact on Ongoing Care

How best to translate genomic discoveries and technological breakthroughs into the clinic? And how to ensure equity of access? This session will offer perspectives from international and national experts traversing the journey from genomic insights to assay development to clinical implementation beyond the "big smoke".

Presenters:
Christina Curtis - Towards forecasting tumour progression: From genomic insights to predictive biomarkers in GI malignancy
Carlos S Cabalag – Circulating tumour DNA as a promising biomarker in Oesophageal Cancer
Kortnye Smith - Access and use of Genomics for patients with GI cancers outside the “big smoke”

Panel discussion
Chairs: Oliver Sieber & Jan Mumford

12.20-13.20 | AEDT

Lunch and Transition to Breakout Rooms

13.20-14.20 | AEDT

Grand Room 1–4

Special Interest Breakout Session 1 Sponsored by Pierre Fabre

Theme: Precision Medicine in mCRC

Chair: Chris Karapetis

Panel: Jayesh Desai, Catherine Mitchell and Jeanne Tie

13.20-14.20 | AEDT

State Rooms 1&2

Special Interest Breakout Session 2 Sponsored by Bristol Myers Squibb

Theme: Navigating the Complexities of Metastatic Gastro-oesophageal Cancer in the IO Era - a Case Based Discussion

Description: The patients you encounter in real life in the clinic are often different from those enrolled in clinical trials. Given the availability of nivolumab in conjunction with chemotherapy for advanced oesophago-gastric cancer, clinicians will need to make practical decisions about immunotherapy treatment and management of toxicities outside a clinical trial protocol. This case based discussion will discuss challenging scenarios faced by clinicians managing patients with advanced oesophago-gastric cancer.

Chair: Niall Tebbutt

Panel: Adnan Nagrial, Amitesh Roy, Jeremy Shapiro and Iris Tung

Followed by panel discussion and Q&A

13.20-14.20 | AEDT

State Room 3

Special Interest Breakout Session 3 Sponsored by Bayer

Theme: Precision Medicine, Genetic Testing, Targeted Therapy & Patient Preselection

Description: Personalised therapy for GI cancers

Chair: Nick Pavlakis

Presentations:
1. Lara Lipton: Genetic testing in Pancreas Cancer
2. Peter Gibbs: CRC Molecular profiling
3. Nick Pavlakis: Cholangiocarcioma: Genetic testing for all?
4. Christine Hemmings: Molecular testing in GI cancers - test methodology and implications
5. Tim Price: Equity and access to Genetic testing in GI cancers. A proposed pragmatic algorithm

Followed by panel discussion

13.20-14.20 | AEDT

Lake Room 1&2

Special Interest Breakout Session 4 sponsored by Lisata Therapeutics

Theme: A Novel Therapeutic for Pancreas Cancer, Emerging Data

Description: Discovery and development of the novel tumor microenvironment targeting peptide CEND-1 (LSTA) – emerging data from patients with pancreatic adenocarcinoma and other GI cancers

Chair: John Zalcberg

Presentations:
1. Kazuki Sugahara: Tumor-penetrating peptides - from discovery to bedside
2. Harri Jarvelainen: The bench to bedside journey of CEND-1
3. Andrew Dean: Engaging immunotherapy for pancreatic cancer- are we on the cusp of success…?

Followed by panel discussion & Q&A

14.20-14.50 | AEDT

Trade Hall

Afternoon Tea

14.50-14.55 | AEDT

Grand Room 1–4

Introduction

MC: Julie McCrossin

14.55-16.15 | AEDT

Grand Room 1–4

New Concepts Symposium Sponsored by AstraZeneca

The New Concepts Symposium is designed as a novel way to reach out to a wider spectrum of the group. This session provides an opportunity for delegates to present embryonic new concepts for feedback and discussion with the audience as well as comments from international guests in terms of perspective, international interest and relevance. A good idea can be tested and a perception gained on whether to take the concept forward to a more formal review by the Upper or Lower GI Working Party. The identification of other AGITG members who may wish to assist in progressing the concept as an AGITG supported protocol is also possible. The winner of the Best New Concept Award will receive a $3,500 prize and a framed certificate. The runner up will receive a $1,500 prize and framed certificate. The Awards are presented at the Annual Scientific Meeting Dinner and details of the Award recipients are published on the AGITG website and in the Annual Report.

Chairs: Chris Karapetis & Lara Lipton

Concept one:
Presenter: Dr Laura Tam
Concept title: BIL-PPP: Combination PD1 and PARP inhibitor as maintenance treatment following platinum-gemcitabine for unresectable locally-advanced or metastatic biliary tract cancers
Invited Faculty Reviewer: Dr Michael Allen

Concept two:
Presenter: Dr Helen Mohan
Concept title: COALA: changing outcomes after low anterior resection – a rectal cancer survivorship trial of pelvic floor prehabilitation prior to reversal of ileostomy
Invited Faculty Reviewer: Dr Tamara Glyn

Concept 3:
Presenter: Dr Anshini Jain
Concept title: PredictOrg: Personalised Intraperitoneal Chemotherapy for Patients with Resectable Colorectal
Invited Faculty Reviewer: Dr Iain Tan

16.15 -17.30 | AEDT

Grand Room 1–4

Best of the Best Posters and Fast Forward - Sponsored by Servier Oncology

The AGITG Annual Scientific Meeting accepts abstracts for posters for selection by the Executive Organising Committee. Posters are displayed in the exhibition area. Four posters are chosen for presentation in the Best of the Best Session. Each presenter has seven minutes to present with three minutes for questions. Four posters are also chosen for Fast Forward presentation. Each presenter has three minutes to present with two minutes for questions. The AGITG recognises excellence in the Posters and Fast Forward Sessions at each annual meeting. The winning presenter in the Posters Session receives a $3,500 prize and framed certificate. The winning presenter in the Fast Forward session receives $1,500 and a framed certificate. The Awards are presented at the Annual Scientific Meeting Dinner and details of the Award recipients are published on the AGITG website and in the Annual Report.

Best of the Best Posters

Initial uptake and impact of immunotherapy in Australian patients with deficient mismatch repair metastatic colorectal cancer
Iris Tung

Local and systemic Programmed Death-1 (PD-1) pathway activity predicts complete response to chemoradiotherapy in locally advanced rectal cancer
Melanie McCoy

Genomic targetability of cholangiocarcinomas and outcomes for Australian patients screened through the Molecular Screening and Therapeutics (MoST) program
Subotheni Thavaneswaran

Left side, RAS wildtype metastatic colorectal cancer (mCRC) – examining real-world first line treatment strategies and outcomes for patients
Jane McKenzie

Fast Forward

Initial Survival Estimates and Conditional Survival Estimates in Early Stage Colorectal Cancer
Matthew Loft

Benefits of Neoadjuvant FOLFIRINOX over upfront resection in borderline resectable pancreatic cancer – an international, multicentre real-world data analysis
Sam Banks

Therapy and molecular characterisation patterns across Australasia: Big data insights from the PURPLE Pancreatic Cancer platform
Belinda Lee

Human Gene and Microbiome Contributions to Radiotherapy Response in Rectal Cancer
Rachel Purcell

Chairs: Jeanne Tie & Amitesh Roy

18.30-19.30 | AEDT

Trade Hall

AGITG 24th Annual Meeting Reception

19.30-22.30 | AEDT

Grand Room 1–4

AGITG 24th Annual Meeting Dinner

Thursday November 17, 2022

07.15-08.45 | AEDT

State Room

Medical Oncology Keynote Breakfast Session – Immunotherapy in gastroesophageal cancers

Oesophagogastric malignancies historically have been treated with either chemotherapy, radiation therapy, surgery, or a combination of all three dependent on the stage of disease. Despite these standard treatments, survival outcomes remain relatively poor. Recent global trials have highlighted the evolving utility of immunotherapy in the treatment of oesophagogastric malignancies. This session explores the evidence and clinical application of immunotherapy in the treatment of both advanced and early stage oesophagogastric malignancy, and how it may shape future management.

Presenters:
Lizzy Smyth - Immunotherapy for Advanced Oesophagogastric Cancers: Where We are and Where We are Going
Amitesh Roy - Immunotherapy in Early Stage Oesophagogastric Cancers: Current and Future Practice

Chairs: Melissa Eastgate & Michael Allen

07.15-08.45 | AEDT

Lake Rooms 1 & 2

Radiation Oncology Keynote Breakfast Session – Upper GI Cancer Focus

This session will explore the indications and potential use of dose escalation in radiotherapy in pancreatic and hepatobiliary cancers. Prof Koay will provide an overview, evidence and challenges for dose escalation in these cancers, followed by discussion of example cases

Presenter:
Eugene Koay - Dose escalation for Pancreatic and Hepatobiliary cancers

Q&A

Chairs: Meredith Johnson & Yuvnik Trada

07.15-08.45 | AEDT

Lake Room 3&4

Surgical Oncology Keynote Breakfast Session – The Latest on Gall Bladder and Pancreatic Cancer

Join us to hear Tim Pawlik discuss the key advances in gallbladder cancer care, the multidisciplinary progress and the advent of neoadjuvant treatment in gallbladder cancer in the US. Hear Jas Samra’s expert opinion on the controversial roles of arterial surgery and divestment and the role of oligometastatic liver surgery in pancreatic cancer. Be the first to hear the latest research progress results on EUS profiling of pancreatic and biliary cancer by Dan Croagh. Support Charles Pilgrim’s Scanpatient trial which will standardise reporting for pancreatic cancer.

Presenters:
Tim Pawlik - Gallbladder Cancer: The Need for a Multi-Disciplinary Approach
Jas Samra – Pancreatic cancer; arteries – Divest / Resect / Don’t, and Isolated / Oligo Pancreatic Liver Mets
Dan Croagh – EUS Molecular Profiling of Pancreatic and Biliary Cancer
Charles Pilgrim – SCANPatient: A Trial of Synoptic Reporting for Pancreas Cancer

08.45-09.00 | AEDT

Transition to Plenary Room

09.00-09.10 | AEDT

Grand Room 1–4

Welcome, Housekeeping and Introduction

MC: Julie McCrossin

09.10-10.00 | AEDT

Grand Room 1–4

AGITG Upper GI Cancer Research Session One

• SSGXXII: Sumitra Ananda
• CONTROL NETs: Nick Pavlakis
• ACME ABC: Dan Croagh

Q&A

Chairs: Lara Lipton & Sweet Ping Ng

10.00-10.30 | AEDT

Trade Hall

Morning Tea

10.30-10.35 | AEDT

Grand Room 1– 4

Welcome back and Introduction

MC: Julie McCrossin

10.35-12.35 | AEDT

Grand Room 1–4

AGITG Upper GI Cancer Research Session Two

• NEO-IMPACT: Lorraine Chantrill
• ASCEND: Andrew Dean
• DYNAMIC-Pancreas: Belinda Lee
• MASTERPLAN: Andrew Oar
• PALEO: Fiona Day
• NEO-CREATE: Amitesh Roy
• TOPGEAR: Trevor Leong
• INTEGRATE IIa/b: Nick Pavlakis

Lizzy Smyth - AGITG Upper GI Cancer Research Portfolio - How Does This Fit into the International Context?

Q&A

Chairs: Ben Lawrence & Shehara Mendis

12:35-13.30 | AEDT

Lunch and move to Special Interest Breakout Sessions

13.30-14.30 | AEDT

State Room 3

Special Interest Breakout Session 5 sponsored by AstraZeneca

Theme: Management of advanced biliary cancer in the era of genomics

Description: Recent advances in understanding of tumour biology and new therapies are changing the landscape in advanced biliary tract cancers (BTC). This session will focus on treatment challenges and emerging therapies for locally advanced/unresectable and metastatic BTC. Overview of multidisciplinary challenges including interventions for biliary patency, and recent and future landscape for systemic therapies. This interdisciplinary session will include updates and time for panel discussion and questions.

Chair: Prof David Goldstein

Presentations
1. Lara Lipton: Molecular Targets in Biliary Tract Cancers biology:
2. Peter Tagkalidis: Current paradigms for biliary stenting
3. Katrin Sjoquist: Emerging therapies and new targets in biliary tract cancers
4. David Goldstein: Biliary Cancer-Immunotherapy

Followed by panel discussion and Q&A.

13.30-14.30 | AEDT

State Rooms 1 & 2

Special Interest Breakout Session 6 sponsored by Viatris

Theme: New research in diagnosis and treatment of pancreatic cancer.

Chair: John Zalcberg

Presentations:
1. Rachael Neale: Towards earlier diagnosis of pancreatic cancer
2. Daniel Croagh: Complexity of modern management of pancreatic cancer (case study)
3. John Zalcberg: Measurement of Real World Outcomes

Followed by panel discussion

13.30-14.30 | AEDT

Grand Room 1–4

Special Interest Breakout Session 7 sponsored by MSD

Theme: Immunotherapy in IL setting of unresectable or metastatic oesophago-gastric cancer

Description: Management update, case studies, panel discussion, followed by Q&A

Chair: Amitesh Roy

Panel: Lorraine Chantrill, Margaret Lee & Nick Pavlakis

13.30-14.30 | AEDT

Lake Rooms 1 & 2

Surgical Workshop – NETs Workshop

Listen to the experts cover a dedicated neuroendocrine session. How far can we go with GEP NET resections and when do we abort? Listen to the advances in managing metastatic neuroendocrine tumours and come hear a challenging case of PNET from our invited faculty.

Presenters:
Saxon Connor - PNET A Challenging Case
Ben Thomson - Management of NET Liver Metastases - Does Grade Matter?
Anubhav Mittal - Is there NET gain?

Chairs: Christopher Lim & Ee Jun Ban

14.30-14.45 | AEDT

Move to Closing Plenary

14.45-16.00 | AEDT

Grand Room 1–4

Closing Plenary – Improving Equity, Diversity and Inclusion in Clinical Trials

The theme for the 2022 AGITG ASM Closing Plenary draws upon the need for equity of access to therapeutic options across regional, rural and remote (RRR) areas, as well as culturally diverse and First Nations populations. Following the global effort to advance equitable cancer care as explored during the 2022 ASCO meeting, concerted efforts to reduce barriers to both patient and trial-centre participation in Australia and New Zealand is a priority.

There are multiple contributing factors that lead to a disparity in representation and access to clinical trials, especially in rural and regional areas. These include reduced capacity and infrastructure at RRR cancer care services, restrictive eligibility criteria, and the increasing complexity of trial designs. Patients seeking to participate in clinical trials face complex barriers too, including geographical distance to the trial centre and the associated expense, limited trial-related literacy, disruption to home and work life, and opposing cultural values. To combat these barriers and facilitate diverse trial participation, new trial models are emerging. Most notably is the Decentralised Clinical Trial model, which includes teletrials and Direct-to-Patient trial models.

Our expert panellists will discuss current and planned initiatives led by the Federal and State Governments to ensure that these populations are better represented in clinical trials. Topics covered will include funding, awareness programs, education and training opportunities, and the role of technology and innovation to improve patient outcomes.

Panel discussion: Christie Ah-Fa, Gail Garvey, Reema Harrison, Narayan Karanth, Abhijit Pal & Sabe Sabesan

Presentation: Dorothy Keefe - CEO Cancer Australia

Facilitators: Julie McCrossin & Rob Ramsay

16.00

Close of ASM

16.15

Bus depart to Airport

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